José A. Centeno
MSc, PhD, FRSC
Adjunct Professor, Department of Chemistry, University of Puerto Rico at Mayaguez, Puerto Rico
Adjunct Professor of Medicine, University of Maryland School of Medicine, Division of Occupational and Environmental Medicine
Professor of Chemistry, Faculty of Chemistry, University of the Republic of Uruguay, Montevideo, Uruguay
Fellow Royal Society of Chemistry, FRSC, London, UK
Honorary Academician, Royal Academy of Medicine and Surgery, Andalucia Oriental, Spain
Founder and Director, International Environmental & Health Sciences Consortium (www.iehsconsortium.org)
Phone (Mobile): +1-301-502-8846
ORCID ID: 0000-0002-1202-0493
Dr. Jose A. Centeno is a Physical Chemist (Toxicologist) by training, with international and nationally recognized expertise in biophysical toxicology, bioanalytical chemistry, environmental and toxicologic pathology, nanotechnology, medical devices, regulatory science and medical geology. He is graduate from the University of Puerto Rico at Mayaguez (BS (Chemistry) and MS (Physical Chemistry), a Ph.D. in Physical Chemistry from Michigan State University and completed a postdoctoral fellowship training in biophysics and chemical pathology at the U.S. Armed Forces Institute of Pathology.
Dr. Centeno has served the US Federal Government in several scientific and senior managerial appointments. Most recently, he served as the Director of the Division of Biology, Chemistry and Materials Science (DBCMS) within the Office of Sciences and Engineering Laboratories (OSEL), Center for Devices and Radiological Health (CDRH), US Food and Drug Administration (USFDA), from June 2015 to December 2019. As DBCMS Director, he had the responsibility of managing and lead a scientific team composed of over 30 senior level government scientists, postdoctoral fellows, students and visiting scientists, as well as overseen all the Division operational activities, budget allocations and laboratory research activities which included research programs in the areas of biocompatibility and toxicology, microbiology and infection control, materials science, and nanotechnology. He served as director of the CDRH-OSEL Advanced Characterization Facility and managed the research and training activities in nanotechnology. As DBCMS Director, Dr. Centeno managed a regulatory research portfolio with over 40 projects aimed at ensuring the safety and efficacy of medical devices. DBCMS research program contributes to regulatory decision-making in CDRH and directly impacts the development of CDRH guidance documents and international standards in the areas of biocompatibility, toxicological risk assessment, and nanotechnology. During his tenure at the FDA, Dr. Centeno represented the Agency in a wide range of national and international regulatory and scientific committees including serving as FDA Primary Liaison to the International Standard Organization Technical Committee on Nanotechnology (ISO TC 229
Nanotechnologies), Chair of the US Technical Advisory Committee (US TAG ISO TC 229 Nanotechnologies) Working Group 5 on “Performance and Applications”, CDRH Delegate to the US Pharmacopeial Convention (USP), and member of the Interagency Working Group on Asbestos in Consumer Products (IWGACP).
Prior to joining the USFDA, Dr. Centeno worked for the U.S. Department of Defense (DoD) for over 25-years, serving as a senior research scientist and Director, Bioinorganic and Metal Toxicology Laboratory for the Armed Forces Institute of Pathology (AFIP). During his tenure with the AFIP/US-DoD, Dr. Centeno worked in developing research and diagnostic areas such as environmental pathology, forensic toxicology analysis, trace element speciation analysis and exposure assessment to toxic metals of military and public health relevance, and applications of bio-spectroscopy studies to better understand foreign body reaction to bio-implantable materials. He established several registries for the study of diseases associated with exposure to chemical, environmental and bio-materials used in medical devices including the National Silicone Breast Implant Registry, the Depleted Uranium Registry, the Tissue and Tumor Repository on Chronic Arsenic Exposure, the Medical Geology Registry, and the DoD Toxic Embedded Fragment Registry. His last DoD assignment was with the Joint Pathology Center (JPC) as Director, Division of Biophysical Toxicology and Depleted Uranium Program, Silver Spring, MD, where he was tasked with developing, implementing and directing a chemical toxicology and bioanalytical program aimed at supporting the clinical research and long-term care decisions for patients affected by embedded metal fragments.
Dr. Centeno has presented over 200 invited seminars and lectures, and he is the principal author and/or co- author of over 100 publications including journal manuscripts, book chapters, reports, monographs, and research abstracts on various topics on metals and metalloids, biomedical spectroscopy, medical geology, environmental toxicology, and public health. He has been involved in numerous academic, government and professional activities related to biomedical research, public health, regulatory sciences, environmental health, medical geology and environmental toxicology including serving as General Chairman of the 6th International Symposium in Metal Ions in Biology and Medicine (ISMIBM) (May 7-10, 2000), and co- chairman of the 7th, 8th, and 9th ISMIBM (2002, 2004 & 2006), participating in several national and international committees including the International Agency for Research on Cancer (IARC Vol 74 (1999), Lyon, France), NIH grant proposal Study Sections, the USEPA TOSCA-Interagency Testing Committee, the International Working Group on Medical Geology, the National Research Council Committee on Research Priorities for Earth Science and Public Health, the National Academies – Board on International Organizations, and the U.S. Department of Defense Working Group on Biomonitoring.
Dr. Centeno is a co-founding member and Past-President of the International Medical Geology Association (www.medicalgeology.org), and he is currently the founder and Director of the International Environmental & Health Sciences Consortium (www.iehsconsortium.org), an international network of scientists supporting research, training and capacity building in the environmental, public health, toxicological and medical geology sciences. He is Fellow of the Royal Society of Chemistry (FRSC), London, UK; Honorary Academician, Royal Academy of Medicine and Surgery (HARAMS), Andalucia Oriental, Spain; and he was recently appointed as Chair on Medical Geology and Director, “Jose A. Centeno International Center on Medical Geology Research” at Nasarawa State University, Keffi, Nigeria. He has served as Regional Officer for the International Union of Geological Sciences and its Commission on Geosciences for Environmental Management (IUGSGEM, 2005), as Senior Advisor for the IUGS- International Year of Planet Earth (2007-2009), and as invited speaker at the US Academy of Sciences, the Swedish Academies of Sciences, and the Academia Sinica, Taiwan, China. He serves on the Editorial Board of two scientific journals, as Associate Editor of the book on Essentials of Medical Geology (1st Edition 2005, 2nd Edition 2013), as Associate Editor of the book Metal Contaminants in New Zealand (2005), and is the founder of the International Medical Geology Conference Series (MEDGEO).
Dr. Centeno has been appointed to several Professorship positions at major national and international universities including Adjunct Professor of Chemistry, Department of Chemistry at the University of Puerto Rico at Mayaguez (2021-present); Adjunct Professor of Medicine, University of Maryland School of Medicine, Division of Occupational and Environmental Medicine (2020-present); Professor (Titular IV), Faculty of Chemistry, Universidad de la Republica de Uruguay, Montevideo, Uruguay (2020- present); Professorial Lecturer of Environmental and Occupational Health, George Washington University-School of Public Health and Health Services; Distinguished Professor – School of Science and Technology at Turabo University-Puerto Rico; Adjunct Professor-School of Science and Technology at Metropolitan University, Puerto Rico; Adjunct Professor, Universidad del Este, Puerto Rico; Adjunct Professor- School of Science and Technology at Jackson State University; Guest Professorship – China University of Mining and Technology, Beijing, China (2002); Williams Evans Visiting Fellow – University of Otago, School of Public Health, Wellington, New Zealand; and Visiting Professor, Chinese Academy of Science, Guiyang, China. He is the recipient of the 2008 Special Recognition Award from the Universidad Metropolitana in Puerto Rico, the 2005 Jackson State University Research and Sponsored Programs Excellence Award, the 1996 and 2003 Superior Civilian Service Award from the Department of the Army, and the 1999 Distinguish Alumni Award on Science from the University of Puerto Rico-Mayaguez.
He has served on the External Advisory Board for several university programs including the National Science Foundation (NSF) Model Institutions of Excellence (MIE) Program at Universidad Metropolitana-PR, US Presidential Advisory Board on Health, Science and Engineering for Ana G. Mendez University System, National Institutes of Health (NIH) Research Centers for Minority Institutions (RCMI) Program at Jackson State University, as Chairman of the NIH “URGREAT-MBRS-RISE” Program for Universidad del Este in Puerto Rico, and as Chairman of the NSF Science and Technology Access to Research and Graduate Education (STARGE) program for Jackson State University.
Over the last two decades, he has focused attention on research and teaching/training activities on regulatory sciences, environmental toxicology, environmental pathology (e.g., tissue reactions from bioimplantable materials), medical geology, and health effects of trace elements, metals and metalloids, and has conducted research and training activities on environmental toxicology and public health in over 50 countries. He has an established worldwide network of research collaborations in the environmental sciences, medical geology and public health fields including: Universidad de la Republica de Uruguay, Montevideo; University of Western Australia, Perth, Australia; Ballarat University, Australia; Canterbury University, Christchurch, New Zealand; University of Otago, School of Public Health, Wellington, New Zealand.
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Selected publications (full list of over 100 publications is available upon request)
- Semen Uranium Concentrations in Depleted Uranium Exposed Gulf War Veterans: Correlations with Other Body Fluid Matrices. McDiarmid MA, Gucer P, Centeno JA, Todorov T, Squibb KS. Biol Trace Elem Res. 2019 Jul;190(1):45-51. doi: 10.1007/s12011-018-1527-3. Epub 2018 Oct 6.
- Cerebrospinal Fluid–Directed rAAV9–rsATP7A Plus Subcutaneous Copper Histidinate Advance Survival and Outcomes in a Menkes Disease Mouse Model. Haddad MR, Choi EY, Zerfas PM, Yi L, Martinelli D, Sullivan P, Goldstein DS, Centeno JA, Brinster LR, Ralle M, Kaler SG. Mol Ther Methods Clin Dev. 2018 Jul 9;10:165-178. doi: 10.1016/j.omtm.2018.07.002. eCollection 2018 Sep 21.
- Public Regulatory Databases as a Source of Insight for Neuromodulation Devices Stimulation Parameters. Kumsa D, Steinke GK, Molnar GF, Hudak EM, Montague FW, Kelley SC, Untereker DF, Shi A, Hahn BP, Condit C, Lee H, Bardot D, Centeno JA, Krauthamer V, Takmakov PA. Neuromodulation. 2018 Feb;21(2):117-125. doi: 10.1111/ner.12641. Epub 2017 Aug 7. Review.
- Metal Exposure in Veterans With Embedded Fragments From War–Related Injuries: Early Findings From Surveillance Efforts. Gaitens JM, Condon M, Squibb KS, Centeno JA, McDiarmid MA. J Occup Environ Med. 2017 Nov;59(11):1056-1062. doi: 10.1097/JOM.0000000000001119.
- The U.S. Department of Veterans’ Affairs depleted uranium exposed cohort at 25 Years: Longitudinal surveillance results. McDiarmid MA, Gaitens JM, Hines S, Condon M, Roth T, Oliver M, Gucer P, Brown L, Centeno JA, Dux M, Squibb KS. Environ Res. 2017 Jan;152:175-184. doi: 10.1016/j.envres.2016.10.016. Epub 2016 Oct 25.
- Mobilization of Metal From Retained Embedded Fragments in a Blast–Injured Iraq War Veteran. Gaitens JM, Centeno JA, Squibb KS, Condon M, McDiarmid MA. Mil Med. 2016 Jun;181(6):e625-9. doi:10.7205/MILMED-D-15-00432.
- Biologic monitoring and surveillance results for the department of veterans affairs’ depleted uranium cohort: Lessons learned from sustained exposure over two decades. McDiarmid MA, Gaitens JM, Hines S, Condon M, Roth T, Oliver M, Gucer P, Brown L, Centeno JA, Streeten E, Squibb KS. Am J Ind Med. 2015 Jun;58(6):583-94. doi: 10.1002/ajim.22435. Epub 2015 Apr 24.
- Molecular and biochemical characterization of Mottled–dappled, an embryonic lethal Menkes disease mouse model. Haddad MR, Patel KD, Sullivan PH, Goldstein DS, Murphy KM, Centeno JA, Kaler SG. Mol Genet Metab. 2014 Dec;113(4):294-300. doi: 10.1016/j.ymgme.2014.10.001. Epub 2014 Oct 13.
- Chapter 4 embedded metal fragments. Kalinich JF, Vane EA, Centeno JA, Gaitens JM, Squibb KS, McDiarmid MA, Kasper CE. Annu Rev Nurs Res. 2014;32:63-78. doi: 10.1891/0739-6686.32.63. Review.
- Embedded fragments from U.S. military personnel––chemical analysis and potential health implications. Centeno JA, Rogers DA, van der Voet GB, Fornero E, Zhang L, Mullick FG, Chapman GD, Olabisi AO, Wagner DJ, Stojadinovic A, Potter BK. Int J Environ Res Public Health. 2014 Jan 23;11(2):1261-78. doi: 10.3390/ijerph110201261.
- Assessment of geographical variation in the respiratory toxicity of desert dust particles. Taylor K, Foster ML, Law JM, Centeno JA, Fornero E, Henderson MS, Trager SA, Stockelman MG, Dorman DC. Inhal Toxicol. 2013 Jun;25(7):405-16. doi: 10.3109/08958378.2013.797524.
- The Gulf War depleted uranium cohort at 20 years: bioassay results and novel approaches to fragment surveillance. McDiarmid MA, Gaitens JM, Hines S, Breyer R, Wong-You-Cheong JJ, Engelhardt SM, Oliver M, Gucer P, Kane R, Cernich A, Kaup B, Hoover D, Gaspari AA, Liu J, Harberts E, Brown L, Centeno JA, Gray PJ, Xu H, Squibb KS. Health Phys. 2013 Apr;104(4):347-61. doi: 10.1097/HP.0b013e31827b1740.
- Arsenic–induced biochemical and genotoxic effects and distribution in tissues of Sprague–Dawley rats. Patlolla AK, Todorov TI, Tchounwou PB, van der Voet G, Centeno JA. Microchem J. 2012 Nov 1;105:101-107. Epub 2012 Sep 3.
- Uranium quantification in semen by inductively coupled plasma mass spectrometry. Todorov TI, Ejnik JW, Guandalini G, Xu H, Hoover D, Anderson L, Squibb K, McDiarmid MA, Centeno JA. J Trace Elem Med Biol. 2013 Jan;27(1):2-6. doi: 10.1016/j.jtemb.2012.07.004. Epub 2012 Sep 1.
- In utero copper treatment for Menkes disease associated with a severe ATP7A mutation. Haddad MR, Macri CJ, Holmes CS, Goldstein DS, Jacobson BE, Centeno JA, Popek EJ, Gahl WA, Kaler SG. Mol Genet Metab. 2012 Sep;107(1-2):222-8. doi: 10.1016/j.ymgme.2012.05.008. Epub 2012 May 18.
- Arsenic–induced health crisis in peri–urban Moyna and Ardebok villages, West Bengal, India: an exposure assessment study. Maity JP, Nath B, Kar S, Chen CY, Banerjee S, Jean JS, Liu MY, Centeno JA, Bhattacharya P, Chang CL, Santra SC. Environ Geochem Health. 2012 Oct;34(5):563-74. doi: 10.1007/s10653-012-9458-y. Epub 2012 May 12.
- Surveillance for long–term health effects associated with depleted uranium exposure and retained embedded fragments in US veterans. Squibb KS, Gaitens JM, Engelhardt S, Centeno JA, Xu H, Gray P, McDiarmid MA. J Occup Environ Med. 2012 Jun;54(6):724-32. doi: 10.1097/JOM.0b013e31824fe138.
- Biological responses in rats exposed to cigarette smoke and Middle East sand (dust). Dorman DC, Mokashi V, Wagner DJ, Olabisi AO, Wong BA, Moss OR, Centeno JA, Guandalini G, Jackson DA, Dennis WE, Lewis JA, Thomas RS, Chapman GD. Inhal Toxicol. 2012;24(2):109-24. doi: 10.3109/08958378.2011.647413.
- ATP7A gene addition to the choroid plexus results in long–term rescue of the lethal copper transport defect in a Menkes disease mouse model. Donsante A, Yi L, Zerfas PM, Brinster LR, Sullivan P, Goldstein DS, Prohaska J, Centeno JA, Rushing E, Kaler SG. Mol Ther. 2011 Dec;19(12):2114-23. doi: 10.1038/mt.2011.143. Epub 2011 Aug 30.
- Biomarkers of mercury exposure in two eastern Ukraine cities. Gibb H, Haver C, Kozlov K, Centeno JA, Jurgenson V, Kolker A, Conko KM, Landa ER, Xu H. J Occup Environ Hyg. 2011 Apr;8(4):187-93. doi: 10.1080/15459624.2011.556984.
- Tissue distribution of tungsten in mice following oral exposure to sodium tungstate. Guandalini GS, Zhang L, Fornero E, Centeno JA, Mokashi VP, Ortiz PA, Stockelman MD, Osterburg AR, Chapman GG. Chem Res Toxicol. 2011 Apr 18;24(4):488-93. doi: 10.1021/tx200011k. Epub 2011 Mar 18.
- Spatial mapping of mineralization with manganese–enhanced magnetic resonance imaging. Chesnick IE, Centeno JA, Todorov TI, Koenig AE, Potter K. Bone. 2011 May 1;48(5):1194-201. doi: 10.1016/j.bone.2011.02.014. Epub 2011 Feb 23.
- Prostate cancer outcome and tissue levels of metal ions. Sarafanov AG, Todorov TI, Centeno JA, Macias V, Gao W, Liang WM, Beam C, Gray MA, Kajdacsy-Balla AA. Prostate. 2011 Aug 1;71(11):1231-8. doi: 10.1002/pros.21339. Epub 2011 Jan 26.
- Lead and copper in pigeons (Columbia livia) exposed to a small arms–range soil. Bannon DI, Parsons PJ, Centeno JA, Lal S, Xu H, Rosencrance AB, Dennis WE, Johnson MS. Arch Environ Contam Toxicol. 2011 Feb;60(2):351-60. doi: 10.1007/s00244-010-9540-3. Epub 2010 Jun 4.
- Combat Wound Initiative program. Stojadinovic A, Elster E, Potter BK, Davis TA, Tadaki DK, Brown TS, Ahlers S, Attinger CE, Andersen RC, Burris D, Centeno J, Champion H, Crumbley DR, Denobile J, Duga M, Dunne JR, Eberhardt J, Ennis WJ, Forsberg JA, Hawksworth J, Helling TS, Lazarus GS, Milner SM, Mullick FG, Owner CR, Pasquina PF, Patel CR, Peoples GE, Nissan A, Ring M, Sandberg GD, Schaden W, Schultz GS, Scofield T, Shawen SB, Sheppard FR, Stannard JP, Weina PJ, Zenilman JM. Mil Med. 2010 Jul;175(7 Suppl):18-24. Review.
- Enzyme stabilization by glass–derived silicates in glass–exposed aqueous solutions. Ives JA, Moffett JR, Arun P, Lam D, Todorov TI, Brothers AB, Anick DJ, Centeno JA, Namboodiri MA, Jonas WB. Homeopathy. 2010 Jan;99(1):15-24. doi: 10.1016/j.homp.2009.11.006.
- Editorial––Introducing a special theme issue on medical geology. Centeno JA. J Environ Monit. 2008 Dec;10(12):1391-3. doi: 10.1039/b817552g. Epub 2008 Nov 5. No abstract available.
- Analysis of iron, zinc, selenium and cadmium in paraffin–embedded prostate tissue specimens using inductively coupled plasma mass–spectrometry. Sarafanov AG, Todorov TI, Kajdacsy-Balla A, Gray MA, Macias V, Centeno JA. J Trace Elem Med Biol. 2008;22(4):305-14. doi: 10.1016/j.jtemb.2008.03.010. Epub 2008 Jul 16.
- Clinical and analytical toxicology of dietary supplements: a case study and a review of the literature. van der Voet GB, Sarafanov A, Todorov TI, Centeno JA, Jonas WB, Ives JA, Mullick FG. Biol Trace Elem Res. 2008 Oct;125(1):1-12. doi: 10.1007/s12011-008-8157-0. Epub 2008 Aug 16. Review.
- Foreword: 10th anniversary review: natural disasters and their long–term impacts on the health of communities. Centeno JA. J Environ Monit. 2008 Feb;10(2):166; discussion 167-75. doi: 10.1039/b800850g. Epub 2008 Jan 21.
- Biomarkers of mercury exposure at a mercury recycling facility in Ukraine. Gibb HJ, Kozlov K, Buckley JP, Centeno J, Jurgenson V, Kolker A, Conko K, Landa E, Panov B, Panov Y, Xu H. J Occup Environ Hyg. 2008 Aug;5(8):483-9. doi: 10.1080/15459620802174432.
- Metals and health: a clinical toxicological perspective on tungsten and review of the literature. van der Voet GB, Todorov TI, Centeno JA, Jonas W, Ives J, Mullick FG. Mil Med. 2007 Sep;172(9):1002-5. Review.
- Manganese–enhanced magnetic resonance microscopy of mineralization. Chesnick IE, Todorov TI, Centeno JA, Newbury DE, Small JA, Potter K. Magn Reson Imaging. 2007 Sep;25(7):1095-104. Epub 2007 Jan 16.
- Health and natural hazards. Centeno JA. Analyst. 2007 Jun;132(6):T47.
- Blackfoot disease in Taiwan: its link with inorganic arsenic exposure from drinking water. Tseng CH, Chong CK, Tseng CP, Centeno JA. Ambio. 2007 Feb;36(1):82-4. Review.
- Global impacts of geogenic arsenic: a medical geology research case. Centeno JA, Tseng CH, Van der Voet GB, Finkelman RB. Ambio. 2007 Feb;36(1):78-81.
- Safety of intracerebroventricular copper histidine in adult rats. Lem KE, Brinster LR, Tjurmina O, Lizak M, Lal S, Centeno JA, Liu PC, Godwin SC, Kaler SG. Mol Genet Metab. 2007 May;91(1):30-6. Epub 2007 Mar 1.
- Environmental exposure to trace elements and prostate cancer in three New Zealand ethnic groups. Gray MA, Centeno JA, Slaney DP, Ejnik JW, Todorov T, Nacey JN. Int J Environ Res Public Health. 2005 Dec;2(3-4):374-84.
- The emerging Medical and Geological Association. Finkelman RB, Centeno JA, Selinus O. Trans Am Clin Climatol Assoc. 2005;116:155-65; discussion 165.
- Dihydroartemisinin is cytotoxic to papillomavirus–expressing epithelial cells in vitro and in vivo. Disbrow GL, Baege AC, Kierpiec KA, Yuan H, Centeno JA, Thibodeaux CA, Hartmann D, Schlegel R. Cancer Res. 2005 Dec 1;65(23):10854-61.
- Distribution of urinary selenium and arsenic among pregnant women exposed to arsenic in drinking water. Christian WJ, Hopenhayn C, Centeno JA, Todorov T. Environ Res. 2006 Jan;100(1):115-22.
- Dihydroartemisinin is cytotoxic to papillomavirus–expressing epithelial cells in vitro and in vivo. Disbrow GL, Baege AC, Kierpiec KA, Yuan H, Centeno JA, Thibodeaux CA, Hartmann D, Schlegel R. Cancer Res. 2005 Dec 1;65(23):10854-61.
- Downregulation of myelination, energy, and translational genes in Menkes disease brain. Liu PC, Chen YW, Centeno JA, Quezado M, Lem K, Kaler SG. Mol Genet Metab. 2005 Aug;85(4):291-300.
- Uranium analysis in urine by inductively coupled plasma dynamic reaction cell mass spectrometry. Ejnik JW, Todorov TI, Mullick FG, Squibb K, McDiarmid MA, Centeno JA. Anal Bioanal Chem. 2005 May;382(1):73-9. Epub 2005 Apr 15.
- Rapid sodium cyanide depletion in cell culture media: outgassing of hydrogen cyanide at physiological pH. Arun P, Moffett JR, Ives JA, Todorov TI, Centeno JA, Namboodiri MA, Jonas WB. Anal Biochem. 2005 Apr 15;339(2):282-9.
- Pathology of lymph nodes from patients with breast implants: a histologic and spectroscopic evaluation. Katzin WE, Centeno JA, Feng LJ, Kiley M, Mullick FG. Am J Surg Pathol. 2005 Apr;29(4):506-11.
- Trends and occupational associations in incidence of hospitalized pulmonary sarcoidosis and other lung diseases in Navy personnel: a 27–year historical prospective study, 1975–2001. Gorham ED, Garland CF, Garland FC, Kaiser K, Travis WD, Centeno JA. Chest. 2004 Nov;126(5):1431-8.
- Arsenic toxicity, mutagenesis, and carcinogenesis––a health risk assessment and management approach. Tchounwou PB, Centeno JA, Patlolla AK. Mol Cell Biochem. 2004 Jan;255(1-2):47-55. Review.
- Environmental toxicology and health effects associated with dinitrotoluene exposure. Tchounwou PB, Newsome C, Glass K, Centeno JA, Leszczynski J, Bryant J, Okoh J, Ishaque A, Brower M. Rev Environ Health. 2003 Jul-Sep;18(3):203-29. Review.
- Carcinogenic and systemic health effects associated with arsenic exposure––a critical review. Tchounwou PB, Patlolla AK, Centeno JA. Toxicol Pathol. 2003 Nov-Dec;31(6):575-88. Review.
- Blood and tissue concentration of cesium after exposure to cesium chloride: a report of two cases. Centeno JA, Pestaner JP, Omalu BI, Torres NL, Field F, Wagner G, Mullick FG. Biol Trace Elem Res. 2003 Aug;94(2):97104.
- Low–Dose Cadmium Exposure Reduces Human Prostate Cell Transformation in Culture and Up–Regulates Metallothionein and MT–1G mRNA. Gaddipati JP, Rajeshkumar NV, Grove JC, Maharaj SV, Centeno JA, Maheshwari RK, Jonas WB. Nonlinearity Biol Toxicol Med. 2003 Apr;1(2):199-212.
- Pathology related to chronic arsenic exposure. Centeno JA, Mullick FG, Martinez L, Page NP, Gibb H, Longfellow D, Thompson C, Ladich ER. Environ Health Perspect. 2002 Oct;110 Suppl 5:883-6.